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Hepatic STAT1-Nuclear Translocation and Interleukin 28B Polymorphisms Predict Treatment Outcomes in Hepatitis C Virus Genotype 1-Infected Patients

BACKGROUND: We investigated associations between signal transducer and activator of transcription (STAT) 1 in pretreated liver tissues, interleukin (IL) 28B polymorphism and treatment response in hepatitis C virus (HCV)-infected patients treated with peginterferon and ribavirin. METHODS AND FINDINGS...

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書目詳細資料
Autores principales: Miyamura, Tatsuo, Kanda, Tatsuo, Nakamoto, Shingo, Wu, Shuang, Fujiwara, Keiichi, Imazeki, Fumio, Yokosuka, Osamu
格式: Online Artículo Texto
語言:English
出版: Public Library of Science 2011
主題:
在線閱讀:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236206/
https://www.ncbi.nlm.nih.gov/pubmed/22174846
http://dx.doi.org/10.1371/journal.pone.0028617