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Surgical Membranes as Directional Delivery Devices to Generate Tissue: Testing in an Ovine Critical Sized Defect Model

PURPOSE: Pluripotent cells residing in the periosteum, a bi-layered membrane enveloping all bones, exhibit a remarkable regenerative capacity to fill in critical sized defects of the ovine femur within two weeks of treatment. Harnessing the regenerative power of the periosteum appears to be limited...

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Detalles Bibliográficos
Autores principales: Knothe Tate, Melissa L., Chang, Hana, Moore, Shannon R., Knothe, Ulf R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236208/
https://www.ncbi.nlm.nih.gov/pubmed/22174873
http://dx.doi.org/10.1371/journal.pone.0028702