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Membrane-Lipid Therapy in Operation: The HSP Co-Inducer BGP-15 Activates Stress Signal Transduction Pathways by Remodeling Plasma Membrane Rafts

Aging and pathophysiological conditions are linked to membrane changes which modulate membrane-controlled molecular switches, causing dysregulated heat shock protein (HSP) expression. HSP co-inducer hydroxylamines such as BGP-15 provide advanced therapeutic candidates for many diseases since they pr...

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Detalles Bibliográficos
Autores principales: Gombos, Imre, Crul, Tim, Piotto, Stefano, Güngör, Burcin, Török, Zsolt, Balogh, Gábor, Péter, Mária, Slotte, J. Peter, Campana, Federica, Pilbat, Ana-Maria, Hunya, Ákos, Tóth, Noémi, Literati-Nagy, Zsuzsanna, Vígh, László, Glatz, Attila, Brameshuber, Mario, Schütz, Gerhard J., Hevener, Andrea, Febbraio, Mark A., Horváth, Ibolya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236211/
https://www.ncbi.nlm.nih.gov/pubmed/22174906
http://dx.doi.org/10.1371/journal.pone.0028818