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Distinct and Overlapping Effector Functions of Expanded Human CD4(+), CD8α(+) and CD4(-)CD8α(-) Invariant Natural Killer T Cells

CD1d-restricted invariant natural killer T (iNKT) cells have diverse immune stimulatory/regulatory activities through their ability to release cytokines and to kill or transactivate other cells. Activation of iNKT cells can protect against multiple diseases in mice but clinical trials in humans have...

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Detalles Bibliográficos
Autores principales: O'Reilly, Vincent, Zeng, Shijuan G., Bricard, Gabriel, Atzberger, Ann, Hogan, Andrew E., Jackson, John, Feighery, Conleth, Porcelli, Steven A., Doherty, Derek G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236218/
https://www.ncbi.nlm.nih.gov/pubmed/22174854
http://dx.doi.org/10.1371/journal.pone.0028648