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Allele-specific regulation of FGFR2 expression is cell type-dependent and may increase breast cancer risk through a paracrine stimulus involving FGF10
INTRODUCTION: SNPs rs2981582 and rs2981578, located in a linkage disequilibrium block (LD block) within intron 2 of the fibroblast growth factor receptor 2 gene (FGFR2), are associated with a mildly increased breast cancer risk. Allele-specific regulation of FGFR2 mRNA expression has been reported p...
Main Authors: | , , , , , , , , , , , , |
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Format: | Online Article Text |
Language: | English |
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BioMed Central
2011
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Subjects: | |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236336/ https://www.ncbi.nlm.nih.gov/pubmed/21767389 http://dx.doi.org/10.1186/bcr2917 |