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NF-kappaB activation within macrophages leads to an anti-tumor phenotype in a mammary tumor lung metastasis model

INTRODUCTION: Metastasis from primary tumor to the lungs is a major cause of the mortality associated with breast cancer. Both immune and inflammatory responses impact whether circulating mammary tumor cells successfully colonize the lungs leading to established metastases. Nuclear factor -kappaB (N...

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Detalles Bibliográficos
Autores principales: Connelly, Linda, Barham, Whitney, Onishko, Halina M, Chen, Lianyi, Sherrill, Taylor P, Zabuawala, Tahera, Ostrowski, Michael C, Blackwell, Timothy S, Yull, Fiona E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236346/
https://www.ncbi.nlm.nih.gov/pubmed/21884585
http://dx.doi.org/10.1186/bcr2935