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PPARγ Promotes Growth and Invasion of Thyroid Cancer Cells

Undifferentiated (anaplastic) thyroid cancer (ATC) is one of the most aggressive human malignancies and no effective therapy is currently available. We show here that PPARγ levels are elevated in cells derived from ATC. Depletion of PPARγ in HTh74 ATC cells resulted in decreased cell growth, cell cy...

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Detalles Bibliográficos
Autores principales: Wood, William M., Sharma, Vibha, Bauerle, Kevin T., Pike, Laura A., Zhou, Qiong, Fretwell, Deborah L., Schweppe, Rebecca E., Haugen, Bryan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236353/
https://www.ncbi.nlm.nih.gov/pubmed/22194735
http://dx.doi.org/10.1155/2011/171765