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IT-141, a Polymer Micelle Encapsulating SN-38, Induces Tumor Regression in Multiple Colorectal Cancer Models

Polymer micelles are promising drug delivery vehicles for the delivery of anticancer agents to tumors. Often, anticancer drugs display potent cytotoxic effects towards cancer cells but are too hydrophobic to be administered in the clinic as a free drug. To address this problem, a polymer micelle was...

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Detalles Bibliográficos
Autores principales: Carie, Adam, Rios-Doria, Jonathan, Costich, Tara, Burke, Brian, Slama, Richard, Skaff, Habib, Sill, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236496/
https://www.ncbi.nlm.nih.gov/pubmed/22187652
http://dx.doi.org/10.1155/2011/869027