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Optimization of Liposomal Lipid Composition for a New, Reactive Sulfur Donor, and In Vivo Efficacy Studies on Mice to Antagonize Cyanide Intoxication

Present studies have focused on a novel cyanide antidotal system, on the coencapsulation of a new sulfur donor DTO with rhodanese within sterically stabilized liposomes. The optimal lipid composition for coencapsulation of DTO with rhodanese is the combination of 1-palmitoyl-2-oleoyl-sn-glycero-3-ph...

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Detalles Bibliográficos
Autores principales: Petrikovics, Ilona, Jayanna, Prashanth, Childress, Jonathan, Budai, Marianna, Martin, Sarah, Kuzmitcheva, Galina, Rockwood, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236500/
https://www.ncbi.nlm.nih.gov/pubmed/22187653
http://dx.doi.org/10.1155/2011/928626