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Higher proportions of circulating FOXP3(+) and CTLA-4(+) regulatory T cells are associated with lower fractions of memory CD4(+) T cells in infants
In adults, a majority of FOXP3(+) T(regs) expresses CTLA-4, and this costimulatory molecule is essential to control the expansion of other T cells. However, it remains to be investigated whether FOXP3(+) and/or CTLA-4(+) T(regs) are associated with the expression of memory markers and homing recepto...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Leukocyte Biology
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236549/ https://www.ncbi.nlm.nih.gov/pubmed/21934066 http://dx.doi.org/10.1189/jlb.0511244 |