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Higher proportions of circulating FOXP3(+) and CTLA-4(+) regulatory T cells are associated with lower fractions of memory CD4(+) T cells in infants

In adults, a majority of FOXP3(+) T(regs) expresses CTLA-4, and this costimulatory molecule is essential to control the expansion of other T cells. However, it remains to be investigated whether FOXP3(+) and/or CTLA-4(+) T(regs) are associated with the expression of memory markers and homing recepto...

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Detalles Bibliográficos
Autores principales: Rabe, Hardis, Lundell, Anna-Carin, Andersson, Kerstin, Adlerberth, Ingegerd, Wold, Agnes E., Rudin, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Leukocyte Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236549/
https://www.ncbi.nlm.nih.gov/pubmed/21934066
http://dx.doi.org/10.1189/jlb.0511244