Hyperactive Neuroendocrine Secretion Causes Size, Feeding, and Metabolic Defects of C. elegans Bardet-Biedl Syndrome Mutants

Bardet-Biedl syndrome, BBS, is a rare autosomal recessive disorder with clinical presentations including polydactyly, retinopathy, hyperphagia, obesity, short stature, cognitive impairment, and developmental delays. Disruptions of BBS proteins in a variety of organisms impair cilia formation and fun...

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Detalles Bibliográficos
Autores principales: Lee, Brian H., Liu, Jason, Wong, Daisy, Srinivasan, Supriya, Ashrafi, Kaveh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236739/
https://www.ncbi.nlm.nih.gov/pubmed/22180729
http://dx.doi.org/10.1371/journal.pbio.1001219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236739/
https://www.ncbi.nlm.nih.gov/pubmed/22180729
http://dx.doi.org/10.1371/journal.pbio.1001219

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