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Sex Effects in Mouse Prion Disease Incubation Time

Prion disease incubation time in mice is determined by many factors including PrP expression level, Prnp alleles, genetic background, prion strain and route of inoculation. Sex differences have been described in age of onset for vCJD and in disease duration for both vCJD and sporadic CJD and have al...

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Detalles Bibliográficos
Autores principales: Akhtar, Shaheen, Wenborn, Adam, Brandner, Sebastian, Collinge, John, Lloyd, Sarah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236759/
https://www.ncbi.nlm.nih.gov/pubmed/22174884
http://dx.doi.org/10.1371/journal.pone.0028741