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Host-Range Restriction of Vaccinia Virus E3L Deletion Mutant Can Be Overcome In Vitro, but Not In Vivo, by Expression of the Influenza Virus NS1 Protein

During the last decades, research focused on vaccinia virus (VACV) pathogenesis has been intensified prompted by its potential beneficial application as a vector for vaccine development and anti-cancer therapies, but also due to the fear of its potential use as a bio-terrorism threat. Recombinant vi...

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Detalles Bibliográficos
Autores principales: Guerra, Susana, Abaitua, Fernando, Martínez-Sobrido, Luis, Esteban, Mariano, García-Sastre, Adolfo, Rodríguez, Dolores
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236761/
https://www.ncbi.nlm.nih.gov/pubmed/22174864
http://dx.doi.org/10.1371/journal.pone.0028677