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Mouse Studies to Shape Clinical Trials for Mitochondrial Diseases: High Fat Diet in Harlequin Mice

BACKGROUND: Therapeutic options in human mitochondrial oxidative phosphorylation (OXPHOS) diseases have been poorly evaluated mostly because of the scarcity of cohorts and the inter-individual variability of disease progression. Thus, while a high fat diet (HFD) is often recommended, data regarding...

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Detalles Bibliográficos
Autores principales: Schiff, Manuel, Bénit, Paule, El-Khoury, Riyad, Schlemmer, Dimitri, Benoist, Jean-François, Rustin, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236768/
https://www.ncbi.nlm.nih.gov/pubmed/22174907
http://dx.doi.org/10.1371/journal.pone.0028823