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First-passage time analysis of a one-dimensional diffusion-reaction model: application to protein transport along DNA

BACKGROUND: Proteins search along the DNA for targets, such as transcription initiation sequences, according to one-dimensional diffusion, which is interrupted by micro- and macro-hopping events and intersegmental transfers that occur under close packing conditions. RESULTS: A one-dimensional diffus...

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Detalles Bibliográficos
Autores principales: Mayo, Michael L, Perkins, Edward J, Ghosh, Preetam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236840/
https://www.ncbi.nlm.nih.gov/pubmed/22165905
http://dx.doi.org/10.1186/1471-2105-12-S10-S18