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Molecular Conversion of Muscarinic Acetylcholine Receptor M(5) to Muscarinic Toxin 7 (MT7)-Binding Protein

Muscarinic toxin 7 (MT7) is a mamba venom peptide that binds selectively to the M(1) muscarinic acetylcholine receptor. We have previously shown that the second (ECL2) and third (ECL3) extracellular loops of the M(1) receptor are critically involved in binding the peptide. In this study we used a mu...

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Detalles Bibliográficos
Autores principales: Rondinelli, Sergio, Näreoja, Katja, Näsman, Johnny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237002/
https://www.ncbi.nlm.nih.gov/pubmed/22174976
http://dx.doi.org/10.3390/toxins3111393