Paxillin Mediates Sensing of Physical Cues and Regulates Directional Cell Motility by Controlling Lamellipodia Positioning

Physical interactions between cells and the extracellular matrix (ECM) guide directional migration by spatially controlling where cells form focal adhesions (FAs), which in turn regulate the extension of motile processes. Here we show that physical control of directional migration requires the FA sc...

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Detalles Bibliográficos
Autores principales: Sero, Julia E., Thodeti, Charles K., Mammoto, Akiko, Bakal, Chris, Thomas, Sheila, Ingber, Donald E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237434/
https://www.ncbi.nlm.nih.gov/pubmed/22194823
http://dx.doi.org/10.1371/journal.pone.0028303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237434/
https://www.ncbi.nlm.nih.gov/pubmed/22194823
http://dx.doi.org/10.1371/journal.pone.0028303

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