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Prisoner's Dilemma in Cancer Metabolism
As tumors outgrow their blood supply and become oxygen deprived, they switch to less energetically efficient but oxygen-independent anaerobic glucose metabolism. However, cancer cells maintain glycolytic phenotype even in the areas of ample oxygen supply (Warburg effect). It has been hypothesized th...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237466/ https://www.ncbi.nlm.nih.gov/pubmed/22194857 http://dx.doi.org/10.1371/journal.pone.0028576 |