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Ursodeoxycholic Acid Is Conjugated with Taurine to Promote Secretin-Stimulated Biliary Hydrocholeresis in the Normal Rat

BACKGROUND & AIMS: Secretin induces bicarbonate-rich hydrocholeresis in healthy individuals, but not in untreated patients with primary biliary cirrhosis (PBC). Ursodeoxycholic acid (UDCA) – the first choice treatment for PBC – restores the secretin response. Compared with humans, secretin has p...

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Detalles Bibliográficos
Autores principales: Úriz, Miriam, Sáez, Elena, Prieto, Jesús, Medina, Juan F., Banales, Jesús M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237485/
https://www.ncbi.nlm.nih.gov/pubmed/22194894
http://dx.doi.org/10.1371/journal.pone.0028717