Interaction between CRHR1 and BDNF Genes Increases the Risk of Recurrent Major Depressive Disorder in Chinese Population

BACKGROUND: An important etiological hypothesis about depression is stress has neurotoxic effects that damage the hippocampal cells. Corticotropin-releasing hormone (CRH) regulates brain-derived neurotrophic factor (BDNF) expression through influencing cAMP and Ca2+ signaling pathways during the cou...

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Detalles Bibliográficos
Autores principales: Xiao, Zheman, Liu, Wanhong, Gao, Kai, Wan, Qirong, Yang, Can, Wang, Huiling, Wang, Xiaoping, Wang, Gaohua, Liu, Zhongchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237493/
https://www.ncbi.nlm.nih.gov/pubmed/22194899
http://dx.doi.org/10.1371/journal.pone.0028733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237493/
https://www.ncbi.nlm.nih.gov/pubmed/22194899
http://dx.doi.org/10.1371/journal.pone.0028733

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