A miR-200b/200c/429-Binding Site Polymorphism in the 3′ Untranslated Region of the AP-2α Gene Is Associated with Cisplatin Resistance

The transcription factor AP-2α functions as a tumor suppressor by regulating various genes that are involved in cell proliferation and apoptosis. Chemotherapeutic drugs including cisplatin induce post-transcriptionally endogenous AP-2α, which contributes to chemosensitivity by enhancing therapy-indu...

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Detalles Bibliográficos
Autores principales: Wu, Yuan, Xiao, Yuzhong, Ding, Xiaofeng, Zhuo, Yiming, Ren, Peng, Zhou, Chang, Zhou, Jianlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237583/
https://www.ncbi.nlm.nih.gov/pubmed/22194984
http://dx.doi.org/10.1371/journal.pone.0029043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237583/
https://www.ncbi.nlm.nih.gov/pubmed/22194984
http://dx.doi.org/10.1371/journal.pone.0029043

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