Expression of B-RAF V600E in Type II Pneumocytes Causes Abnormalities in Alveolar Formation, Airspace Enlargement and Tumor Formation in Mice

Growth factor induced signaling cascades are key regulatory elements in tissue development, maintenance and regeneration. Perturbations of these cascades have severe consequences, leading to developmental disorders and neoplastic diseases. As a major function in signal transduction, activating mutat...

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Detalles Bibliográficos
Autores principales: Zanucco, Emanuele, Götz, Rudolf, Potapenko, Tamara, Carraretto, Irene, Ceteci, Semra, Ceteci, Fatih, Seeger, Werner, Savai, Rajkumar, Rapp, Ulf R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237599/
https://www.ncbi.nlm.nih.gov/pubmed/22194995
http://dx.doi.org/10.1371/journal.pone.0029093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237599/
https://www.ncbi.nlm.nih.gov/pubmed/22194995
http://dx.doi.org/10.1371/journal.pone.0029093

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