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LPA Is a Chemorepellent for B16 Melanoma Cells: Action through the cAMP-Elevating LPA(5) Receptor
Lysophosphatidic acid (LPA), a lipid mediator enriched in serum, stimulates cell migration, proliferation and other functions in many cell types. LPA acts on six known G protein-coupled receptors, termed LPA(1–6), showing both overlapping and distinct signaling properties. Here we show that, unexpec...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237609/ https://www.ncbi.nlm.nih.gov/pubmed/22195035 http://dx.doi.org/10.1371/journal.pone.0029260 |