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Low oxygen levels induce the expression of the embryonic morphogen Nodal

Low oxygen (O(2)) levels characterize the microenvironment of both stem cells and rapidly growing tumors. Moreover, hypoxia is associated with the maintenance of stem cell–like phenotypes and increased invasion, angiogenesis and metastasis in cancer patients. Metastatic cancers, such as breast cance...

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Detalles Bibliográficos
Autores principales: Quail, Daniela F., Taylor, Meghan J., Walsh, Logan A., Dieters-Castator, Dylan, Das, Padmalaya, Jewer, Michael, Zhang, Guihua, Postovit, Lynne-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237624/
https://www.ncbi.nlm.nih.gov/pubmed/22031289
http://dx.doi.org/10.1091/mbc.E11-03-0263