Splice variant–specific cellular function of the formin INF2 in maintenance of Golgi architecture

INF2 is a unique formin that can both polymerize and depolymerize actin filaments. Mutations in INF2 cause the kidney disease focal and segmental glomerulosclerosis. INF2 can be expressed as two C-terminal splice variants: CAAX and non-CAAX. The CAAX isoform contains a C-terminal prenyl group and is...

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Detalles Bibliográficos
Autores principales: Ramabhadran, Vinay, Korobova, Farida, Rahme, Gilbert J., Higgs, Henry N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237625/
https://www.ncbi.nlm.nih.gov/pubmed/21998196
http://dx.doi.org/10.1091/mbc.E11-05-0457

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237625/
https://www.ncbi.nlm.nih.gov/pubmed/21998196
http://dx.doi.org/10.1091/mbc.E11-05-0457

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