The schizophrenia susceptibility factor dysbindin and its associated complex sort cargoes from cell bodies to the synapse

Dysbindin assembles into the biogenesis of lysosome-related organelles complex 1 (BLOC-1), which interacts with the adaptor protein complex 3 (AP-3), mediating a common endosome-trafficking route. Deficiencies in AP-3 and BLOC-1 affect synaptic vesicle composition. However, whether AP-3-BLOC-1–depen...

Descripción completa

Detalles Bibliográficos
Autores principales: Larimore, Jennifer, Tornieri, Karine, Ryder, Pearl V., Gokhale, Avanti, Zlatic, Stephanie A., Craige, Branch, Lee, Joshua D., Talbot, Konrad, Pare, Jean-Francois, Smith, Yoland, Faundez, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237628/
https://www.ncbi.nlm.nih.gov/pubmed/21998198
http://dx.doi.org/10.1091/mbc.E11-07-0592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237628/
https://www.ncbi.nlm.nih.gov/pubmed/21998198
http://dx.doi.org/10.1091/mbc.E11-07-0592

Ejemplares similares