Gipr Is Essential for Adrenocortical Steroidogenesis; However, Corticosterone Deficiency Does Not Mediate the Favorable Metabolic Phenotype of Gipr(−/−) Mice

Glucose-dependent insulinotropic polypeptide (GIP) promotes glucose-dependent insulin secretion. However, GIP also enhances glucocorticoid secretion and promotes adiposity. Because obesity and diabetes are glucocorticoid dependent, we examined whether the effects of GIP on energy balance and glycemi...

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Detalles Bibliográficos
Autores principales: Bates, Holly E., Campbell, Jonathan E., Ussher, John R., Baggio, Laurie L., Maida, Adriano, Seino, Yutaka, Drucker, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237652/
https://www.ncbi.nlm.nih.gov/pubmed/22043004
http://dx.doi.org/10.2337/db11-1060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237652/
https://www.ncbi.nlm.nih.gov/pubmed/22043004
http://dx.doi.org/10.2337/db11-1060

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