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Central Role for Interleukin-2 in Type 1 Diabetes

Type 1 diabetes presents clinically with overt hyperglycemia resulting from progressive immune-mediated destruction of pancreatic β-cells and associated metabolic dysfunction. Combined genetic and immunological studies now highlight deficiencies in both the interleukin-2 (IL-2) receptor and its down...

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Detalles Bibliográficos
Autores principales: Hulme, Maigan A., Wasserfall, Clive H., Atkinson, Mark A., Brusko, Todd M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237657/
https://www.ncbi.nlm.nih.gov/pubmed/22187370
http://dx.doi.org/10.2337/db11-1213