Cellular Mechanisms of Restored β-Cell Tolerance Mediated by Protective Alleles of Idd3 and Idd5

Type 1 diabetes genes within the interleukin (IL)-2, cytotoxic T-lymphocyte--associated protein 4 (CTLA-4), and natural resistance-associated macrophage protein (NRAMP1) pathways influence development of autoimmune diabetes in humans and NOD mice. In NOD mice, when present together, protective allel...

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Detalles Bibliográficos
Autores principales: Hamilton-Williams, Emma E., Cheung, Jocelyn, Rainbow, Daniel B., Hunter, Kara M., Wicker, Linda S., Sherman, Linda A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Immunology and Transplantation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237671/
https://www.ncbi.nlm.nih.gov/pubmed/22106155
http://dx.doi.org/10.2337/db11-0790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237671/
https://www.ncbi.nlm.nih.gov/pubmed/22106155
http://dx.doi.org/10.2337/db11-0790

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