Manganese superoxide dismutase is a mitochondrial fidelity protein that protects Polγ against UV-induced inactivation

Manganese superoxide dismutase is a nuclear encoded primary antioxidant enzyme localized exclusively in the mitochondrial matrix. Genotoxic agents, such as UV radiation, generates oxidative stress and cause mitochondrial DNA (mtDNA) damage. The mitochondrial DNA polymerase (Polγ), a major constituen...

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Detalles Bibliográficos
Autores principales: Bakthavatchalu, Vasudevan, Dey, Swatee, Xu, Yong, Noel, Teresa, Jungsuwadee, Paiboon, Holley, Aaron K., Dhar, Sanjit K., Batinic-Haberle, Ines, St Clair, Daret K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237716/
https://www.ncbi.nlm.nih.gov/pubmed/21909133
http://dx.doi.org/10.1038/onc.2011.407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237716/
https://www.ncbi.nlm.nih.gov/pubmed/21909133
http://dx.doi.org/10.1038/onc.2011.407

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