Aspartate(112) is the Selectivity Filter of the Human Voltage Gated Proton Channel

The ion selectivity of pumps and channels is central to their ability to perform a multitude of functions. Here we investigate the mechanism of the extraordinary selectivity of the human voltage gated proton channel(1), hH(V)1. This selectivity is essential to its ability to regulate reactive oxygen...

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Detalles Bibliográficos
Autores principales: Musset, Boris, Smith, Susan M.E., Rajan, Sindhu, Morgan, Deri, Cherny, Vladimir V., DeCoursey, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237871/
https://www.ncbi.nlm.nih.gov/pubmed/22020278
http://dx.doi.org/10.1038/nature10557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237871/
https://www.ncbi.nlm.nih.gov/pubmed/22020278
http://dx.doi.org/10.1038/nature10557

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