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Gender-Specific Mechanism of Synaptic Impairment and Its Prevention by GCSF in a Mouse Model of ALS

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease of motoneurons which progresses differentially in males and females for unknown reason. Here we measured gender differences in pre- and post-synaptic parameters of the neuromuscular transmission in a mutant G93A-SOD1 mouse model of A...

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Detalles Bibliográficos
Autores principales: Naumenko, Nikolay, Pollari, Eveliina, Kurronen, Antti, Giniatullina, Raisa, Shakirzyanova, Anastasia, Magga, Johanna, Koistinaho, Jari, Giniatullin, Rashid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3238042/
https://www.ncbi.nlm.nih.gov/pubmed/22180738
http://dx.doi.org/10.3389/fncel.2011.00026