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How does infliximab work in rheumatoid arthritis?

Since the initial characterization of tumor necrosis factor alpha (TNFα), it has become clear that TNFα has diverse biologic activity. The realization that TNFα plays a role in rheumatoid arthritis (RA) has led to the development of anti-TNF agents for the treatment of RA. Infliximab, a chimeric mon...

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Detalles Bibliográficos
Autores principales: Maini, Ravinder N, Feldmann, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3238217/
https://www.ncbi.nlm.nih.gov/pubmed/12110154
http://dx.doi.org/10.1186/ar549