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Biological effect of varying peptide binding affinity to the BoLA-DRB3*2703 allele

MHC class I and II molecules are immunoregulatory cell surface glycoproteins, which selectively bind to and present antigenic peptides to T-lymphocytes. Murine and human studies show that variable peptide binding affinity to MHC II molecules influences Th1/Th2 responses by inducing distinctive cytok...

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Detalles Bibliográficos
Autores principales: Alizadeh, Zahra, Karrow, Niel, Mallard, Bonnie A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3238229/
https://www.ncbi.nlm.nih.gov/pubmed/12927080
http://dx.doi.org/10.1186/1297-9686-35-S1-S51