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Endoplasmic Reticulum Stress and Lipid Metabolism: Mechanisms and Therapeutic Potential

The endoplasmic reticulum (ER) plays a crucial role in protein folding, assembly, and secretion. Disruption of ER homeostasis may lead to accumulation of misfolded or unfolded proteins in the ER lumen, a condition referred to as ER stress. In response to ER stress, a signal transduction pathway know...

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Detalles Bibliográficos
Autores principales: Basseri, Sana, Austin, Richard C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3238353/
https://www.ncbi.nlm.nih.gov/pubmed/22195283
http://dx.doi.org/10.1155/2012/841362