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Endoplasmic Reticulum Stress and Lipid Metabolism: Mechanisms and Therapeutic Potential
The endoplasmic reticulum (ER) plays a crucial role in protein folding, assembly, and secretion. Disruption of ER homeostasis may lead to accumulation of misfolded or unfolded proteins in the ER lumen, a condition referred to as ER stress. In response to ER stress, a signal transduction pathway know...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3238353/ https://www.ncbi.nlm.nih.gov/pubmed/22195283 http://dx.doi.org/10.1155/2012/841362 |