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Oxaliplatin-Induced Neuropathy in Colorectal Cancer

Oxaliplatin use in palliative and adjuvant treatment of colon cancer is frequently limited by cumulative neurotoxicity, leading to reduced quality of life and decreased dose. The mechanism of this neurotoxicity is unclear, but may relate to neuronal voltage-gated sodium channels involving calcium ch...

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Detalles Bibliográficos
Autores principales: Weickhardt, Andrew, Wells, Keith, Messersmith, Wells
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3238400/
https://www.ncbi.nlm.nih.gov/pubmed/22203844
http://dx.doi.org/10.1155/2011/201593