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Correlation between the type of bcr-abl transcripts and blood cell counts in chronic myeloid leukemia – a possible influence of mdr1 gene expression

The impact of BCR-ABL mRNA type (b3a2 vs. b2a2) on chronic myeloid leukemia (CML) phenotype is still a subject of controversies. We searched for a correlation between the BCR-ABL transcripts type and CML patients' characteristics, including MDR1 gene expression. Ninety-eight untreated chronic p...

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Detalles Bibliográficos
Autores principales: Balatzenko, Gueorgui, Vundinti, Babu Rao, Margarita, Guenova
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3238477/
https://www.ncbi.nlm.nih.gov/pubmed/22184525
http://dx.doi.org/10.4081/hr.2011.e3