Cargando…

Simplified RNA secondary structure mapping by automation of SHAPE data analysis

SHAPE (Selective 2′-hydroxyl acylation analysed by primer extension) technology has emerged as one of the leading methods of determining RNA secondary structure at the nucleotide level. A significant bottleneck in using SHAPE is the complex and time-consuming data processing that is required. We pre...

Descripción completa

Detalles Bibliográficos
Autores principales: Pang, Phillip S., Elazar, Menashe, Pham, Edward A., Glenn, Jeffrey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239176/
https://www.ncbi.nlm.nih.gov/pubmed/21965531
http://dx.doi.org/10.1093/nar/gkr773