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Evolution of the deaminase fold and multiple origins of eukaryotic editing and mutagenic nucleic acid deaminases from bacterial toxin systems

The deaminase-like fold includes, in addition to nucleic acid/nucleotide deaminases, several catalytic domains such as the JAB domain, and others involved in nucleotide and ADP-ribose metabolism. Using sensitive sequence and structural comparison methods, we develop a comprehensive natural classific...

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Detalles Bibliográficos
Autores principales: Iyer, Lakshminarayan M., Zhang, Dapeng, Rogozin, Igor B., Aravind, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239186/
https://www.ncbi.nlm.nih.gov/pubmed/21890906
http://dx.doi.org/10.1093/nar/gkr691