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Evolution of the deaminase fold and multiple origins of eukaryotic editing and mutagenic nucleic acid deaminases from bacterial toxin systems
The deaminase-like fold includes, in addition to nucleic acid/nucleotide deaminases, several catalytic domains such as the JAB domain, and others involved in nucleotide and ADP-ribose metabolism. Using sensitive sequence and structural comparison methods, we develop a comprehensive natural classific...
Autores principales: | Iyer, Lakshminarayan M., Zhang, Dapeng, Rogozin, Igor B., Aravind, L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239186/ https://www.ncbi.nlm.nih.gov/pubmed/21890906 http://dx.doi.org/10.1093/nar/gkr691 |
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