Novel dimeric structure of phage ϕ29-encoded protein p56: insights into uracil-DNA glycosylase inhibition

Protein p56 encoded by the Bacillus subtilis phage ϕ29 inhibits the host uracil-DNA glycosylase (UDG) activity. To get insights into the structural basis for this inhibition, the NMR solution structure of p56 has been determined. The inhibitor defines a novel dimeric fold, stabilized by a combinatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Asensio, Juan Luis, Pérez-Lago, Laura, Lázaro, José M., González, Carlos, Serrano-Heras, Gemma, Salas, Margarita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239192/
https://www.ncbi.nlm.nih.gov/pubmed/21890898
http://dx.doi.org/10.1093/nar/gkr667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239192/
https://www.ncbi.nlm.nih.gov/pubmed/21890898
http://dx.doi.org/10.1093/nar/gkr667

Ejemplares similares