Complexity in the binding of minor groove agents: netropsin has two thermodynamically different DNA binding modes at a single site

Structural results with minor groove binding agents, such as netropsin, have provided detailed, atomic level views of DNA molecular recognition. Solution studies, however, indicate that there is complexity in the binding of minor groove agents to a single site. Netropsin, for example, has two DNA bi...

Descripción completa

Detalles Bibliográficos
Autores principales: Lewis, Edwin A., Munde, Manoj, Wang, Shuo, Rettig, Michael, Le, Vu, Machha, Venkata, Wilson, W. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239193/
https://www.ncbi.nlm.nih.gov/pubmed/21890907
http://dx.doi.org/10.1093/nar/gkr699

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239193/
https://www.ncbi.nlm.nih.gov/pubmed/21890907
http://dx.doi.org/10.1093/nar/gkr699

Ejemplares similares