Guiding strand passage: DNA-induced movement of the gyrase C-terminal domains defines an early step in the supercoiling cycle

DNA gyrase catalyzes ATP-dependent negative supercoiling of DNA in a strand passage mechanism. A double-stranded segment of DNA, the T-segment, is passed through the gap in a transiently cleaved G-segment by coordinated closing and opening of three protein interfaces in gyrase. T-segment capture is...

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Detalles Bibliográficos
Autores principales: Lanz, Martin A., Klostermeier, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239214/
https://www.ncbi.nlm.nih.gov/pubmed/21880594
http://dx.doi.org/10.1093/nar/gkr680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239214/
https://www.ncbi.nlm.nih.gov/pubmed/21880594
http://dx.doi.org/10.1093/nar/gkr680

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