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Clustered ChIP-Seq-defined transcription factor binding sites and histone modifications map distinct classes of regulatory elements
BACKGROUND: Transcription factor binding to DNA requires both an appropriate binding element and suitably open chromatin, which together help to define regulatory elements within the genome. Current methods of identifying regulatory elements, such as promoters or enhancers, typically rely on sequenc...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239327/ https://www.ncbi.nlm.nih.gov/pubmed/22115494 http://dx.doi.org/10.1186/1741-7007-9-80 |