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Combined molecular dynamics and continuum solvent studies of the pre-pore Cry4Aa trimer suggest its stability in solution and how it may form pore

Cry4Aa toxin is one of the highly specific mosquito-larvicidal proteins produced by the bacterium Bacillus thuringiensis subspecies israelensis. It is thought to form pores in the larval midgut membrane that cause membrane leakage and subsequent insect death. Therefore, Cry4Aa and other Cry toxins h...

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Detalles Bibliográficos
Autores principales: Taveecharoenkool, Taveechai, Angsuthanasombat, Chanan, Kanchanawarin, Chalermpol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239330/
https://www.ncbi.nlm.nih.gov/pubmed/20465833
http://dx.doi.org/10.1186/1757-5036-3-10