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A new weapon against an old target

High expression of folate receptors is characteristic for the effector cell population of synovial macrophages in synovial inflammation. A new drug conjugate, EC0746, targets the folate inhibitor aminopterin to folate receptors. In vitro studies show that this conjugate acts antiproliferatively and...

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Detalles Bibliográficos
Autor principal:	Fiehn, Christoph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Editorial
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239345/ https://www.ncbi.nlm.nih.gov/pubmed/21861856 http://dx.doi.org/10.1186/ar3392

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