Targeting metabolism with arsenic trioxide and dichloroacetate in breast cancer cells

BACKGROUND: Cancer cells have a different metabolic profile compared to normal cells. The Warburg effect (increased aerobic glycolysis) and glutaminolysis (increased mitochondrial activity from glutamine catabolism) are well known hallmarks of cancer and are accompanied by increased lactate producti...

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Detalles Bibliográficos
Autores principales: Sun, Ramon C, Board, Philip G, Blackburn, Anneke C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240126/
https://www.ncbi.nlm.nih.gov/pubmed/22093145
http://dx.doi.org/10.1186/1476-4598-10-142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240126/
https://www.ncbi.nlm.nih.gov/pubmed/22093145
http://dx.doi.org/10.1186/1476-4598-10-142

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