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Targeting metabolism with arsenic trioxide and dichloroacetate in breast cancer cells
BACKGROUND: Cancer cells have a different metabolic profile compared to normal cells. The Warburg effect (increased aerobic glycolysis) and glutaminolysis (increased mitochondrial activity from glutamine catabolism) are well known hallmarks of cancer and are accompanied by increased lactate producti...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240126/ https://www.ncbi.nlm.nih.gov/pubmed/22093145 http://dx.doi.org/10.1186/1476-4598-10-142 |