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Insights into integrin-ligand binding and activation from the first crystal structure

CHAPTER SUMMARY: Integrin receptors transduce bidirectional signals between extracellular adhesion molecules and intracellular cytoskeletal and signalling molecules. The structural basis of integrin signalling is unknown, but the recent publication of the first crystal structure of the extracellular...

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Detalles Bibliográficos
Autor principal: Humphries, Martin J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240139/
https://www.ncbi.nlm.nih.gov/pubmed/12110125
http://dx.doi.org/10.1186/ar563