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Insights into integrin-ligand binding and activation from the first crystal structure
CHAPTER SUMMARY: Integrin receptors transduce bidirectional signals between extracellular adhesion molecules and intracellular cytoskeletal and signalling molecules. The structural basis of integrin signalling is unknown, but the recent publication of the first crystal structure of the extracellular...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2002
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240139/ https://www.ncbi.nlm.nih.gov/pubmed/12110125 http://dx.doi.org/10.1186/ar563 |