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Engineering of tissue inhibitor of metalloproteinases mutants as potential therapeutics

CHAPTER SUMMARY: Matrix metalloproteinases (MMPs) play a central role in many biological processes such as development, morphogenesis and wound healing, but their unbalanced activities are implicated in numerous disease processes such as arthritis, cancer metastasis, atherosclerosis, nephritis and f...

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Detalles Bibliográficos
Autores principales: Nagase, Hideaki, Brew, Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240149/
https://www.ncbi.nlm.nih.gov/pubmed/12110123
http://dx.doi.org/10.1186/ar573